Isotretinoin 20 mg

Isotretinoin 20 mg – Oral Retinoid for Severe Acne Treatment

Isotretinoin 20 mg is a powerful oral retinoid medication primarily prescribed for severe nodular acne that has not responded to conventional therapies such as antibiotics or topical treatments. It works by targeting multiple causes of acne including excess sebum production, abnormal skin cell shedding, inflammation, and bacterial colonization, leading to significant and often lasting improvement.

How It Works:
Isotretinoin is a synthetic derivative of vitamin A that reduces the size and output of sebaceous glands, decreases skin cell stickiness, and has anti-inflammatory effects. These combined actions reduce acne lesions, prevent new breakouts, and minimize the risk of scarring.

Indications:

• Severe nodular acne resistant to other treatments

• Cystic acne

• Acne causing physical or psychological distress

Key Benefits:

• Addresses all major causes of acne for comprehensive treatment

• Often results in long-term remission after a treatment course

• Helps prevent acne scars and pigmentation

• Oral administration ensures systemic effectiveness

Dosage and Administration:
Typical dosing ranges from 0.5 to 1 mg/kg/day divided into two doses, usually for 15 to 20 weeks, under strict medical supervision. Dose adjustments depend on patient response and tolerance. Regular monitoring of liver function, lipid levels, and pregnancy status is essential due to potential side effects.

Possible Side Effects:

• Dry skin, lips, and eyes

• Increased sensitivity to sunlight

• Elevated liver enzymes and blood lipids

• Birth defects if taken during pregnancy (strict pregnancy prevention required)

• Mood changes or headaches (rare)

Patients must follow all prescribed guidelines and attend regular follow-ups during treatment.

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